Spotlight on Corneal Infections and Microbiology Department

Corneal infections or Microbial Keratitis is a potentially sight threatening condition of the cornea which can be acute or chronic, transient or recurrent, rapidly or slowly growing, with predilection to involve either the centre or margins of the cornea depending upon the causative organism. It can be caused by a variety of pathogens like bacteria, fungi, viruses and protozoa, though bacteria are the commonest pathogens causing vision threatening conditions. Early diagnosis, which is primarily clinical and substantiated largely by microbiological identification of the pathogen, and prompt treatment are needed to minimise the possibility of permanent visual that loss and reduce structural damage to the cornea.

Epidemiological data reveals universal occurrence of microbial keratitis though factors that influence the prevalence of microbial keratitis and its pathogenesis vary from region to region. They include use of contact lenses, ocular surface diseases, corneal trauma, use of immunosuppressive medications and post ocular surgery especially corneal graft.

In developed countries, contact lens related corneal ulcers in the general population are on the rise, while in developing countries trauma is the most common cause. With advances in the understanding of its pathogenesis, laboratory investigations like immunohistochemistry, fluorescent microscopy, enzyme immunoassays and molecular biology, and the availability of fourth generation antibiotics, the overall visual outcome in bacterial keratitis has improved with time. However, availability of the microbiology services and treatment which require multiple follow ups in India is still a challenge. Thus the incidence of microbial keratitis has been increasing despite availability of newer modalities of treatment.

In this issue of TKCI newsletter, we will have a look at the holistic approach TKCI is taking to combat this menace.


For more information about the Ocular Microbiology and Immunology Diagnostic Services please click here


For more information about the Services Provided to TKCI by JMC please click here


For more information about the No. of TKCI Patients Served by Jhaveri Microbiology Centre, Feb - June 2016 please click here




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